| Accession | TIGR03708 |
| Name | poly_P_AMP_trns |
| Function | polyphosphate:AMP phosphotransferase |
| Gene Symbol | pap |
| Trusted Cutoff | 547.65 |
| Domain Trusted Cutoff | 547.65 |
| Noise Cutoff | 459.10 |
| Domain Noise Cutoff | 459.10 |
| Isology Type | equivalog |
| EC Number | 2.7.4.- |
| HMM Length | 493 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Phosphorus compounds |
| Gene Ontology Term | GO:0005575: cellular_component cellular_component |
| | GO:0006797: polyphosphate metabolic process biological_process |
| | GO:0043751: polyphosphate:AMP phosphotransferase activity molecular_function |
| Author | Haft DH |
| Entry Date | Jan 23 2009 3:59PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family contain a domain duplication. The characterized member from Acinetobacter johnsonii is polyphosphate:AMP phosphotransferase (PAP), which can transfer the terminal phosphate from poly(P) to AMP, yielding ADP. In the opposite direction, this enzyme can synthesize poly(P). Each domain of this protein family is homologous to polyphosphate kinase, an enzyme that can run in the forward direction to extend a polyphosphate chain with a new terminal phosphate from ATP, or in reverse to make ATP (or GTP) from ADP (or GDP). |
| References | RN [1]
RM PMID:15262957
RT Polyphosphate synthetic activity of polyphosphate:AMP phosphotransferase in Acinetobacter johnsonii 210A.
RA Itoh H, Shiba T
RL J Bacteriol. 2004 Aug;186(15):5178-81. |
| Genome Property | GenProp0840: polyphosphate kinase/exopolyphosphatase system (HMM) |
