| Accession | TIGR03707 |
| Name | PPK2_P_aer |
| Function | polyphosphate kinase 2 |
| Gene Symbol | ppk2 |
| Trusted Cutoff | 301.80 |
| Domain Trusted Cutoff | 301.80 |
| Noise Cutoff | 248.45 |
| Domain Noise Cutoff | 248.45 |
| Isology Type | equivalog |
| EC Number | 2.7.4.1 |
| HMM Length | 230 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Phosphorus compounds |
| Gene Ontology Term | GO:0005575: cellular_component cellular_component |
| | GO:0006793: phosphorus metabolic process biological_process |
| | GO:0008976: polyphosphate kinase activity molecular_function |
| Author | Haft DH |
| Entry Date | Jan 23 2009 2:11PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are designated polyphosphate kinase 2 (PPK2) after the characterized protein in Pseudomonas aeruginosa. This family comprises one of three well-separated clades in the larger family described by Pfam model PF03976. PA0141 from this family has been shown capable of operating in reverse, with GDP preferred (over ADP) as a substrate, producing GTP (or ATP) by transfer of a phosphate residue from polyphosphate. Most species with a member of this family also encode a polyphosphate kinase 1 (PPK1). |
| References | RN [1]
RM PMID:12482933
RT Polyphosphate kinase (PPK2), a potent, polyphosphate-driven generator of GTP.
RA Ishige K, Zhang H, Kornberg A
RL Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16684-8. |
| Genome Property | GenProp0840: polyphosphate kinase/exopolyphosphatase system (HMM) |
