| Accession | TIGR03705 |
| Name | poly_P_kin |
| Function | polyphosphate kinase 1 |
| Gene Symbol | ppk1 |
| Trusted Cutoff | 465.85 |
| Domain Trusted Cutoff | 465.85 |
| Noise Cutoff | 241.75 |
| Domain Noise Cutoff | 241.75 |
| Isology Type | equivalog |
| EC Number | 2.7.4.1 |
| HMM Length | 673 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Phosphorus compounds |
| Gene Ontology Term | GO:0006799: polyphosphate biosynthetic process biological_process |
| | GO:0008976: polyphosphate kinase activity molecular_function |
| | GO:0009358: polyphosphate kinase complex cellular_component |
| Author | Haft DH |
| Entry Date | Jan 22 2009 1:03PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are the enzyme polyphosphate kinase 1 (PPK1). This family is found in many prokaryotes and also in Dictyostelium. Sequences in the seed alignment were taken from prokaryotic consecutive two-gene pairs in which the other gene encodes an exopolyphosphatase. It synthesizes polyphosphate from the terminal phosphate of ATP but not GTP, in contrast to PPK2. |
| References | RN [1]
RM PMID:2164013
RT Polyphosphate kinase from Escherichia coli. Purification and demonstration of a phosphoenzyme intermediate.
RA Ahn K, Kornberg A
RL J Biol Chem. 1990 Jul 15;265(20):11734-9.
RN [2]
RM PMID:15520374
RT Inorganic polyphosphate in the origin and survival of species.
RA Brown MR, Kornberg A
RL Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16085-7. |
| Genome Property | GenProp0840: polyphosphate kinase/exopolyphosphatase system (HMM) |
