HMM Summary Page: TIGR03701

Functionmenaquinone biosynthesis decarboxylase, SCO4490 family
Trusted Cutoff495.90
Domain Trusted Cutoff495.90
Noise Cutoff490.95
Domain Noise Cutoff490.95
Isology Typeequivalog
HMM Length433
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryMenaquinone and ubiquinone
Gene Ontology TermGO:0009234: menaquinone biosynthetic process biological_process
GO:0016831: carboxy-lyase activity molecular_function
AuthorHaft DH
Entry DateNov 18 2008 5:05PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are putative decarboxylases involved in a late stage of the alternative pathway for menaquinone, via futalosine, as in Streptomyces coelicolor and Helicobacter pylori.
ReferencesRN [1] RM PMID:18801996 RT An alternative menaquinone biosynthetic pathway operating in microorganisms. RA Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T RL Science. 2008 Sep 19;321(5896):1670-3.
Genome PropertyGenProp0829: menaquinone biosynthesis via futalosine (HMM)