HMM Summary Page: TIGR03700

Functionputative menaquinone biosynthesis radical SAM enzyme, SCO4494 family
Trusted Cutoff434.55
Domain Trusted Cutoff434.55
Noise Cutoff422.35
Domain Noise Cutoff422.35
Isology Typeequivalog
HMM Length351
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryMenaquinone and ubiquinone
Gene Ontology TermGO:0009234: menaquinone biosynthetic process biological_process
AuthorHaft DH
Entry DateNov 18 2008 2:20PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family appear to be involved in menaquinone biosynthesis by an alternate pathway via futalosine, based on close phylogenetic correlation with known markers of the futalosine pathway, gene clustering in many organisms, and paralogy with the SCO4550 protein.
ReferencesRN [1] RM PMID:18801996 RT An alternative menaquinone biosynthetic pathway operating in microorganisms. RA Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T RL Science. 2008 Sep 19;321(5896):1670-3.
Genome PropertyGenProp0829: menaquinone biosynthesis via futalosine (HMM)