HMM Summary Page: TIGR03698

Functionclan AA aspartic protease, AF_0612 family
Trusted Cutoff57.35
Domain Trusted Cutoff57.35
Noise Cutoff42.35
Domain Noise Cutoff42.35
Isology Typesubfamily
EC Number3.4.23.-
HMM Length107
Mainrole CategoryProtein fate
Subrole CategoryDegradation of proteins, peptides, and glycopeptides
Gene Ontology TermGO:0004190: aspartic-type endopeptidase activity molecular_function
GO:0008150: biological_process biological_process
AuthorHaft DH
Entry DateNov 14 2008 2:02PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are clan AA aspartic proteases, related to family TIGR02281. These proteins resemble retropepsins, pepsin-like proteases of retroviruses such as HIV. Members of this family are found in archaea and bacteria.
ReferencesRN [1] RM PMID:19173708 RT Bioinformatic flowchart and database to investigate the origins and diversity of clan AA peptidases. RA Llorens C, Futami R, Renaud G, Moya A RL Biol Direct. 2009 Jan 27;4:3.