Accession | TIGR03697 |
Name | NtcA_cyano |
Function | global nitrogen regulator NtcA |
Gene Symbol | ntcA |
Trusted Cutoff | 244.95 |
Domain Trusted Cutoff | 244.95 |
Noise Cutoff | 227.45 |
Domain Noise Cutoff | 227.45 |
Isology Type | equivalog |
HMM Length | 193 |
Mainrole Category | Regulatory functions |
Subrole Category | DNA interactions |
Gene Ontology Term | GO:0003677: DNA binding molecular_function |
| GO:0003700: sequence-specific DNA binding transcription factor activity molecular_function |
| GO:0006355: regulation of transcription, DNA-dependent biological_process |
| GO:0006808: regulation of nitrogen utilization biological_process |
Author | Haft DH |
Entry Date | Nov 14 2008 1:09PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this protein family, found in the cyanobacteria, are the global nitrogen regulator NtcA. This DNA-binding transcriptional regulator is required for expressing many different ammonia-repressible genes. The consensus NtcA-binding site is G T A N(8)T A C. |
References | RN [1]
RM PMID:8366058
RT General distribution of the nitrogen control gene ntcA in cyanobacteria.
RA Frias JE, Merida A, Herrero A, Martin-Nieto J, Flores E
RL J Bacteriol. 1993 Sep;175(17):5710-3.
RN [2]
RM PMID:18805988
RT Role of two NtcA-binding sites in the complex ntcA gene promoter of the heterocyst-forming cyanobacterium Anabaena sp. strain PCC 7120.
RA Olmedo-Verd E, Valladares A, Flores E, Herrero A, Muro-Pastor AM
RL J Bacteriol. 2008 Nov;190(22):7584-90. |