HMM Summary Page: TIGR03679

FunctionarCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein
Trusted Cutoff197.30
Domain Trusted Cutoff197.30
Noise Cutoff193.45
Domain Noise Cutoff193.45
Isology Typeequivalog
HMM Length218
AuthorSelengut J
Entry DateOct 27 2008 2:17PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein consists of an N-terminal possible metal-binding domain (PF04068) followed by a 4Fe-4S cluster binding domain (PF00037) followed by a C-terminal ABC transporter, ATP-binding domain (PF00005). This combination of N-terminal domains is observed in the RNase L inhibitor, RLI [1]. This model has the same scope as an archaeal COG (arCOG00187) [2] and is found in all completely sequenced archaea and does not recognize any known non-archaeal genes.
ReferencesRN [1] RM PMID: 9524254 RT cDNA cloning and expression analysis of the murine RT ribonuclease L inhibitor. RA Benoit De Coignac A, Bisbal C, Lebleu B, Salehzada T; RL Gene 1998;209:149-156. RN [2] RM PMID:18042280 RT Clusters of orthologous genes for 41 archaeal genomes and implications for evolutionary genomics of archaea. RA Makarova KS, Sorokin AV, Novichkov PS, Wolf YI, Koonin EV RL Biol Direct. 2007 Nov 27;2:33.
Genome PropertyGenProp0831: archaeal core gene set, exactly 1 per genome (HMM)