HMM Summary Page: TIGR03675

FunctionarCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein
Trusted Cutoff580.20
Domain Trusted Cutoff580.20
Noise Cutoff580.00
Domain Noise Cutoff580.00
Isology Typeequivalog
HMM Length631
AuthorSelengut J
Entry DateOct 22 2008 1:23PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family of proteins is universal in the archaea and consistsof an N-terminal type-1 KH-domain (PF00013) a central beta-lactamase-domain (PF00753) with a C-terminal motif associated with RNA metabolism (PF07521). KH-domains are associated with RNA-binding, so taken together, this protein is a likely metal-dependent RNAase. This family was defined in [1] as arCOG01782.
ReferencesRN [1] RM PMID:18042280 RT Clusters of orthologous genes for 41 archaeal genomes and implications for evolutionary genomics of archaea. RA Makarova KS, Sorokin AV, Novichkov PS, Wolf YI, Koonin EV RL Biol Direct. 2007 Nov 27;2:33.
Genome PropertyGenProp0831: archaeal core gene set, exactly 1 per genome (HMM)