| Accession | TIGR03668 |
| Name | Rv0121_F420 |
| Function | PPOX class probable F420-dependent enzyme, Rv0121 family |
| Trusted Cutoff | 119.15 |
| Domain Trusted Cutoff | 119.15 |
| Noise Cutoff | 77.50 |
| Domain Noise Cutoff | 77.50 |
| Isology Type | hypoth_equivalog |
| HMM Length | 141 |
| Author | Haft DH |
| Entry Date | Oct 20 2008 8:11AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. |
| References | RN [1]
RM PMID:20675471
RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria.
RA Selengut JD, Haft DH
RL J Bacteriol. 2010 Nov;192(21):5788-98.
RN [2]
RM PMID:16930487
RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic.
RA Haft DH, Paulsen IT, Ward N, Selengut JD
RL BMC Biol. 2006 Aug 24;4:29. |
| Genome Property | GenProp0002: coenzyme F420 utilization (HMM) |
