HMM Summary Page: TIGR03664
| Accession | TIGR03664 |
| Name | fut_nucase |
| Function | futalosine hydrolase |
| Gene Symbol | mqnB |
| Trusted Cutoff | 124.70 |
| Domain Trusted Cutoff | 124.70 |
| Noise Cutoff | 102.55 |
| Domain Noise Cutoff | 102.55 |
| Isology Type | equivalog |
| EC Number | 3.2.2.26 |
| HMM Length | 228 |
| Author | Selengut J |
| Entry Date | Sep 29 2008 9:36AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme catalyzes the conversion of futalosine to de-hypoxanthine futalosine in a pathway for the biosynthesis of menaquinone [1] distinct from the pathway observed in E. coli. |
| References | RN [1] RM PMID:18801996 RT An alternative menaquinone biosynthetic pathway operating in microorganisms. RA Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T RL Science. 2008 Sep 19;321(5896):1670-3. RN [2] RM PMID:19420717 RT Enzymatic properties of futalosine hydrolase, an enzyme essential to a newly identified menaquinone biosynthetic pathway. RA Hiratsuka T, Itoh N, Seto H, Dairi T RL Biosci Biotechnol Biochem. 2009 May;73(5):1137-41 |
| Genome Property | GenProp0829: menaquinone biosynthesis via futalosine (HMM) |