HMM Summary Page: TIGR03655

Functionrestriction alleviation protein, Lar family
Trusted Cutoff39.60
Domain Trusted Cutoff39.60
Noise Cutoff37.00
Domain Noise Cutoff37.00
Isology Typesubfamily
HMM Length55
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryProphage functions
AuthorHaft DH
Entry DateSep 3 2008 9:10AM
Last ModifiedFeb 14 2011 3:27PM
CommentRestriction alleviation proteins provide a countermeasure to host cell restriction enzyme defense against foreign DNA such as phage or plasmids. This family consists of homologs to the phage antirestriction protein Lar, and most members belong to phage genomes or prophage regions of bacterial genomes.
ReferencesRN [1] RM PMID:7476171 RT Restriction alleviation and modification enhancement by the Rac prophage of Escherichia coli K-12. RA King G, Murray NE RL Mol Microbiol. 1995 May;16(4):769-77.