| Accession | TIGR03652 |
| Name | FeS_repair_RIC |
| Function | iron-sulfur cluster repair di-iron protein |
| Gene Symbol | ric |
| Trusted Cutoff | 204.70 |
| Domain Trusted Cutoff | 204.70 |
| Noise Cutoff | 99.10 |
| Domain Noise Cutoff | 99.10 |
| Isology Type | equivalog |
| HMM Length | 216 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0005506: iron ion binding molecular_function |
| | GO:0030091: protein repair biological_process |
| | GO:0051186: cofactor metabolic process biological_process |
| Author | Haft DH |
| Entry Date | Aug 27 2008 4:12PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family, designated variously as YftE, NorA, DrnN, and NipC, are di-iron proteins involved in the repair of iron-sulfur clusters. Previously assigned names reflect pleiotropic effects of damage from NO or other oxidative stress when this protein is mutated. The suggested name now is RIC, for Repair of Iron Centers. |
| References | RN [1]
RM PMID:18203837
RT Widespread distribution in pathogenic bacteria of di-iron proteins that repair oxidative and nitrosative damage to iron-sulfur centers.
RA Overton TW, Justino MC, Li Y, Baptista JM, Melo AM, Cole JA, Saraiva LM
RL J Bacteriol. 2008 Mar;190(6):2004-13. |
