HMM Summary Page: TIGR03639

FunctionCRISPR-associated endonuclease Cas1, subtype II/NMENI
Gene Symbolcas1
Trusted Cutoff120.00
Domain Trusted Cutoff120.00
Noise Cutoff110.00
Domain Noise Cutoff110.00
Isology Typeexception
EC Number3.1.-.-
HMM Length278
AuthorHaft DH
Entry DateJul 1 2008 3:44PM
Last ModifiedJul 11 2011 9:25AM
CommentThe CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.
ReferencesRN [1] RM PMID:16292354 RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. RA Haft DH, Selengut J, Mongodin EF, Nelson KE RL PLoS Comput Biol. 2005 Nov;1(6):e60. Epub 2005 Nov 11.
Genome PropertyGenProp0314: CRISPR system, II/Nmeni subtype (HMM)