HMM Summary Page: TIGR03613

Functionpyrimidine utilization regulatory protein R
Gene SymbolrutR
Trusted Cutoff368.00
Domain Trusted Cutoff368.00
Noise Cutoff362.00
Domain Noise Cutoff362.00
Isology Typeequivalog
HMM Length202
AuthorSelengut J
Entry DateJun 9 2008 1:02PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein is observed in operons extremely similar to that characterized in E. coli K-12 [1] responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the TetR family of transcriptional regulators defined by the N-teminal model PF00440 and the C-terminal model PF08362 (YcdC-like protein, C-terminal region).
ReferencesRN [1] RM PMID:16540542 RT A previously undescribed pathway for pyrimidine catabolism. RA Loh KD, Gyaneshwar P, Markenscoff Papadimitriou E, Fong R, Kim KS, Parales R, Zhou Z, Inwood W, Kustu S RL Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5114-9. Epub 2006 Mar 15.
Genome PropertyGenProp0813: pyrimidine utilization operon, RutABCDEFGR (HMM)