HMM Summary Page: TIGR03609

Functionpolysaccharide pyruvyl transferase CsaB
Gene SymbolcsaB
Trusted Cutoff213.10
Domain Trusted Cutoff213.10
Noise Cutoff145.65
Domain Noise Cutoff145.65
Isology Typeequivalog
EC Number2.-.-.-
HMM Length301
Mainrole CategoryCell envelope
Subrole CategorySurface structures
Gene Ontology TermGO:0042545: cell wall modification biological_process
GO:0046919: pyruvyltransferase activity molecular_function
AuthorHaft DH
Entry DateMay 8 2008 2:42PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe CsaB protein (cell surface anchoring B) of Bacillus anthracis adds a pyruvoyl group to peptidoglycan-associated polysaccharide. This addition is required for proteins with an S-layer homology domain (PF00395) to bind. Within the larger group of proteins described by Pfam model PF04230, this model represents a distinct clade that nearly exactly follows the phylogenetic distribution of the S-layer homology domain (PF00395).
ReferencesRN [1] RM PMID:10970841 RT Bacterial SLH domain proteins are non-covalently anchored to the cell surface via a conserved mechanism involving wall polysaccharide pyruvylation. RA Mesnage S, Fontaine T, Mignot T, Delepierre M, Mock M, Fouet A RL EMBO J. 2000 Sep 1;19(17):4473-84.
Genome PropertyGenProp0811: S-layer homology domain-mediated cell wall binding (HMM)