| Accession | TIGR03594 |
| Name | GTPase_EngA |
| Function | ribosome-associated GTPase EngA |
| Gene Symbol | engA |
| Trusted Cutoff | 306.70 |
| Domain Trusted Cutoff | 306.70 |
| Noise Cutoff | 230.20 |
| Domain Noise Cutoff | 230.20 |
| Isology Type | equivalog |
| HMM Length | 432 |
| Mainrole Category | Protein synthesis |
| Subrole Category | Other |
| Gene Ontology Term | GO:0003924: GTPase activity molecular_function |
| | GO:0005525: GTP binding molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0042254: ribosome biogenesis biological_process |
| | GO:0043022: ribosome binding molecular_function |
| Author | Haft DH |
| Entry Date | Apr 15 2008 11:32AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | EngA (YfgK, Der) is a ribosome-associated essential GTPase with a duplication of its GTP-binding domain. It is broadly to universally distributed among bacteria. It appears to function in ribosome biogenesis or stability. |
| References | RN [1]
RM PMID:16963571
RT Cooperative and critical roles for both G domains in the GTPase activity and cellular function of ribosome-associated Escherichia coli EngA.
RA Bharat A, Jiang M, Sullivan SM, Maddock JR, Brown ED
RL J Bacteriol. 2006 Nov;188(22):7992-6.
RN [2]
RM PMID:17905831
RT Functional analysis of the GTPases EngA and YhbZ encoded by Salmonella typhimurium.
RA Lamb HK, Thompson P, Elliott C, Charles IG, Richards J, Lockyer M, Watkins N, Nichols C, Stammers DK, Bagshaw CR, Cooper A, Hawkins AR
RL Protein Sci. 2007 Nov;16(11):2391-402. |
| Genome Property | GenProp0802: ribosome biogenesis proteins, bacteria (HMM) |
| | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |
