HMM Summary Page: TIGR03591

Functionpolyribonucleotide nucleotidyltransferase
Gene Symbolpnp
Trusted Cutoff525.05
Domain Trusted Cutoff525.05
Noise Cutoff344.60
Domain Noise Cutoff344.60
Isology Typeequivalog
EC Number2.7.7.8
HMM Length689
Mainrole CategoryTranscription
Subrole CategoryDegradation of RNA
Gene Ontology TermGO:0004654: polyribonucleotide nucleotidyltransferase activity molecular_function
GO:0006402: mRNA catabolic process biological_process
AuthorHaft DH
Entry DateApr 10 2008 10:23AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are polyribonucleotide nucleotidyltransferase, also called polynucleotide phosphorylase. Some members have been shown also to have additional functions as guanosine pentaphosphate synthetase and as poly(A) polymerase (see model TIGR02696 for an exception clade, within this family).
ReferencesRN [1] RM PMID:17965156 RT Kinetics of polynucleotide phosphorylase: comparison of enzymes from Streptomyces and Escherichia coli and effects of nucleoside diphosphates. RA Chang SA, Cozad M, Mackie GA, Jones GH RL J Bacteriol. 2008 Jan;190(1):98-106.