HMM Summary Page: TIGR03590

FunctionUDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase
Gene SymbolpseG
Trusted Cutoff153.55
Domain Trusted Cutoff153.55
Noise Cutoff152.90
Domain Noise Cutoff152.90
Isology Typeequivalog
EC Number3.6.1.57
HMM Length280
AuthorSelengut J, Haft DH
Entry DateApr 9 2008 3:03PM
Last ModifiedJan 27 2014 11:12AM
CommentThis protein is found in association with enzymes involved in the biosynthesis of pseudaminic acid [1], a component of polysaccharide in certain Pseudomonas strains as well as a modification of flagellin in Campylobacter and Hellicobacter [1]. The role of this protein is unclear, although it may participate in N-acetylation in conjunction with, or in the absence of PseH (TIGR03585) as it often scores above the trusted cutoff to PF00583 representing a family of acetyltransferases.
ReferencesRN [1] RM PMID:19483088 RT Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway. RA Rangarajan ES, Proteau A, Cui Q, Logan SM, Potetinova Z, Whitfield D, Purisima EO, Cygler M, Matte A, Sulea T, Schoenhofen IC RL J Biol Chem. 2009 Jul 31;284(31):20989-1000. doi: 10.1074/jbc.M109.012351. RN [2] RM PMID:16684771 RT Functional characterization of the flagellar glycosylation locus in Campylobacter jejuni 81-176 using a focused metabolomics approach. RA McNally DJ, Hui JP, Aubry AJ, Mui KK, Guerry P, Brisson JR, Logan SM, Soo EC RL J Biol Chem. 2006 Jul 7;281(27):18489-98. Epub 2006 May 9.
Genome PropertyGenProp0796: CMP-pseudaminic acid biosynthesis from UDP-N-acetylglucosamine (HMM)