HMM Summary Page: TIGR03584
| Accession | TIGR03584 |
| Name | PseF |
| Function | pseudaminic acid cytidylyltransferase |
| Gene Symbol | pseF |
| Trusted Cutoff | 205.70 |
| Domain Trusted Cutoff | 205.70 |
| Noise Cutoff | 199.80 |
| Domain Noise Cutoff | 199.80 |
| Isology Type | equivalog |
| EC Number | 2.7.7.81 |
| HMM Length | 222 |
| Author | Selengut J |
| Entry Date | Apr 8 2008 5:04PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The sequences in this family include the PF02348 (cytidyltransferase) domain and are homologous to the NeuA protein responsible for the transfer of CMP to neuraminic acid. According to [1], this gene is responsible for the transfer of CMP to the structurally related sugar, pseudaminic acid which is observed as a component of sugar modifications of flagellin in Campylobacter species. This gene is commonly observed in apparent operons with other genes responsible for the biosynthesis of pseudaminic acid and as a component of flagellar and exopolysaccharide biosynthesis loci. |
| References | RN [1] RM PMID:16684771 RT Functional characterization of the flagellar glycosylation locus in Campylobacter jejuni 81-176 using a focused metabolomics approach. RA McNally DJ, Hui JP, Aubry AJ, Mui KK, Guerry P, Brisson JR, Logan SM, Soo EC RL J Biol Chem. 2006 Jul 7;281(27):18489-98. Epub 2006 May 9. |
| Genome Property | GenProp0796: CMP-pseudaminic acid biosynthesis from UDP-N-acetylglucosamine (HMM) |