| Accession | TIGR03576 |
| Name | pyridox_MJ0158 |
| Function | pyridoxal phosphate enzyme, MJ0158 family |
| Trusted Cutoff | 304.45 |
| Domain Trusted Cutoff | 304.45 |
| Noise Cutoff | 96.10 |
| Domain Noise Cutoff | 96.10 |
| Isology Type | hypoth_equivalog |
| HMM Length | 346 |
| Mainrole Category | Unknown function |
| Subrole Category | Enzymes of unknown specificity |
| Author | Haft DH |
| Entry Date | Apr 8 2008 9:40AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this archaeal protein family are pyridoxal phosphate enzymes of unknown function. Sequence similarity to SelA, a bacterial enzyme of selenocysteine biosynthesis, has led to some members being misannotated as functionally equivalent, but selenocysteine is made on tRNA in Archaea by a two-step process that does not involve a SelA homolog. |
| References | RN [1]
RM PMID:16201757
RT Structural and functional investigation of a putative archaeal selenocysteine synthase.
RA Kaiser JT, Gromadski K, Rother M, Engelhardt H, Rodnina MV, Wahl MC
RL Biochemistry. 2005 Oct 11;44(40):13315-27. |
