HMM Summary Page: TIGR03567

FunctionFMN reductase
Gene SymbolssuE
Trusted Cutoff164.05
Domain Trusted Cutoff164.05
Noise Cutoff112.25
Domain Noise Cutoff112.25
Isology Typeequivalog
EC Number1.5.1.38
HMM Length171
Mainrole CategoryCentral intermediary metabolism
Subrole CategorySulfur metabolism
Gene Ontology TermGO:0008752: FMN reductase activity molecular_function
GO:0044273: sulfur compound catabolic process biological_process
GO:0055114: oxidation-reduction process biological_process
AuthorHaft DH
Entry DateMar 19 2008 9:21AM
Last ModifiedJul 28 2012 7:56PM
CommentMembers of this protein family use NAD(P)H to reduce FMN and regenerate FMNH2. Members include the homodimeric, NAD(P)H-dependent enzyme SsuE from Escherichia coli, which serves as a partner to an FMNH2-dependent alkanesulfonate monooxygenase. It is induced by sulfate starvation. The NADH-dependent enzyme MsuE from Pseudomonas aeruginosa is outside the scope of this model (see model TIGR03566).
ReferencesRN [1] RM PMID:17289450 RT Mechanism of flavin reduction in the alkanesulfonate monooxygenase system. RA Gao B, Ellis HR RL Biochim Biophys Acta. 2007 Mar;1774(3):359-67. RN [2] RM PMID:10480865 RT Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli. RA Eichhorn E, van der Ploeg JR, Leisinger T RL J Biol Chem. 1999 Sep 17;274(38):26639-46.