HMM Summary Page: TIGR03562

Functionperoxiredoxin, OsmC subfamily
Trusted Cutoff85.80
Domain Trusted Cutoff85.80
Noise Cutoff84.80
Domain Noise Cutoff84.80
Isology Typesubfamily
HMM Length137
Mainrole CategoryCellular processes
Subrole CategoryDetoxification
Gene Ontology TermGO:0004601: peroxidase activity molecular_function
GO:0006979: response to oxidative stress biological_process
AuthorHaft DH
Entry DateMar 13 2008 2:12PM
Last ModifiedFeb 14 2011 3:27PM
CommentPfam model PF02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein OsmC, or osmotically induced protein C. The member from Thermus thermophilus was shown to have hydroperoxide peroxidase activity. In many species, this protein is induced by stress and helps resist oxidative stress.
ReferencesRN [1] RM PMID:18084893 RT Peroxiredoxins in bacterial antioxidant defense. RA Dubbs JM, Mongkolsuk S RL Subcell Biochem. 2007;44:143-93.