HMM Summary Page: TIGR03559

Functionprobable F420-dependent oxidoreductase, Rv3520c family
Trusted Cutoff335.00
Domain Trusted Cutoff335.00
Noise Cutoff221.10
Domain Noise Cutoff221.10
Isology Typesubfamily
HMM Length325
Mainrole CategoryUnknown function
Subrole CategoryEnzymes of unknown specificity
Gene Ontology TermGO:0008150: biological_process biological_process
GO:0016491: oxidoreductase activity molecular_function
AuthorHaft DH
Entry DateMar 13 2008 10:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are predicted to be oxidoreductases dependent on coenzyme F420. The family includes a single member in Mycobacterium tuberculosis (Rv3520c/MT3621) but four in Mycobacterium smegmatis. Prediction that this family is F420-dependent is based primarily on Partial Phylogenetic Profiling vs. F420 biosynthesis.
ReferencesRN [1] RM PMID:20675471 RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria. RA Selengut JD, Haft DH RL J Bacteriol. 2010 Nov;192(21):5788-98.
Genome PropertyGenProp0002: coenzyme F420 utilization (HMM)