HMM Summary Page: TIGR03557

FunctionF420-dependent oxidoreductase, G6PDH family
Trusted Cutoff210.40
Domain Trusted Cutoff210.40
Noise Cutoff128.40
Domain Noise Cutoff128.40
Isology Typesubfamily
EC Number1.-.-.-
HMM Length316
Mainrole CategoryUnknown function
Subrole CategoryEnzymes of unknown specificity
Gene Ontology TermGO:0008150: biological_process biological_process
GO:0016491: oxidoreductase activity molecular_function
AuthorHaft DH
Entry DateMar 6 2008 4:25PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family include F420-dependent glucose-6-phosphate dehydrogenases (TIGR03554) and related proteins. All members of this family come from species that synthesize coenzyme F420, with the exception of those that belong to TIGR03885, a clade within this family in which cofactor binding may instead be directed to FMN.
ReferencesRN [1] RM PMID:20675471 RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria. RA Selengut JD, Haft DH RL J Bacteriol. 2010 Nov;192(21):5788-98. RN [2] RM PMID:23110042 RT Tat-dependent translocation of an F420-binding protein of Mycobacterium tuberculosis. RA Bashiri G, Perkowski EF, Turner AP, Feltcher ME, Braunstein M, Baker EN RL PLoS One. 2012;7(10):e45003. doi: 10.1371/journal.pone.0045003.
Genome PropertyGenProp0002: coenzyme F420 utilization (HMM)