| Accession | TIGR03551 |
| Name | F420_cofH |
| Function | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit |
| Gene Symbol | cofH |
| Trusted Cutoff | 374.10 |
| Domain Trusted Cutoff | 374.10 |
| Noise Cutoff | 369.75 |
| Domain Noise Cutoff | 369.75 |
| Isology Type | equivalog_domain |
| EC Number | 2.5.1.77 |
| HMM Length | 345 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0009108: coenzyme biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Feb 29 2008 2:54PM |
| Last Modified | Dec 12 2011 10:27PM |
| Comment | This enzyme, together with CofG, complete the biosynthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, the chromophore of coenzyme F420. The chromophore is also used in cyanobacteria DNA photolyases. |
| References | RN [1]
RM PMID:14593448
RT Identification of the 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase required for coenzyme F(420) biosynthesis.
RA Graham DE, Xu H, White RH
RL Arch Microbiol. 2003 Dec;180(6):455-64. Epub 2003 Oct 31. |
| Genome Property | GenProp0792: 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) biosynthesis (HMM) |
