HMM Summary Page: TIGR03551

Function7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit
Gene SymbolcofH
Trusted Cutoff374.10
Domain Trusted Cutoff374.10
Noise Cutoff369.75
Domain Noise Cutoff369.75
Isology Typeequivalog_domain
EC Number2.5.1.77
HMM Length345
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0009108: coenzyme biosynthetic process biological_process
AuthorHaft DH
Entry DateFeb 29 2008 2:54PM
Last ModifiedDec 12 2011 10:27PM
CommentThis enzyme, together with CofG, complete the biosynthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, the chromophore of coenzyme F420. The chromophore is also used in cyanobacteria DNA photolyases.
ReferencesRN [1] RM PMID:14593448 RT Identification of the 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase required for coenzyme F(420) biosynthesis. RA Graham DE, Xu H, White RH RL Arch Microbiol. 2003 Dec;180(6):455-64. Epub 2003 Oct 31.
Genome PropertyGenProp0792: 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) biosynthesis (HMM)