HMM Summary Page: TIGR03523

Functiongliding motility associated protein GldN
Gene SymbolgldN
Trusted Cutoff85.90
Domain Trusted Cutoff85.90
Noise Cutoff84.70
Domain Noise Cutoff84.70
Isology Typesubfamily
HMM Length280
AuthorSelengut J
Entry DateDec 18 2007 11:23AM
Last ModifiedFeb 28 2011 3:21PM
CommentMembers of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldN is a protein linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldN abolish the gliding phenotype [1]. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein also include those which are not believed to express the gliding phenotype, such as Prevotella intermedia and Porphyromonas gingivales.
ReferencesRN [1] RM PMID:16199564 RT Flavobacterium johnsoniae gliding motility genes identified by mariner mutagenesis. RA Braun TF, Khubbar MK, Saffarini DA, McBride MJ RL J Bacteriol. 2005 Oct;187(20):6943-52.
Genome PropertyGenProp0781: gliding motility, Bacteroidetes type (HMM)