HMM Summary Page: TIGR03522

Functiongliding motility-associated ABC transporter ATP-binding subunit GldA
Gene SymbolgldA
Trusted Cutoff402.60
Domain Trusted Cutoff402.60
Noise Cutoff362.20
Domain Noise Cutoff362.20
Isology Typeequivalog
HMM Length301
AuthorSelengut J
Entry DateDec 18 2007 10:56AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldA is an ABC transporter ATP-binding protein (PF00005) linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldA abolish the gliding phenotype [1]. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.
ReferencesRN [1] RM PMID:9342376 RT Cloning and characterization of the Flavobacterium johnsoniae (Cytophaga johnsonae) gliding motility gene, gldA. RA Agarwal S, Hunnicutt DW, McBride MJ RL Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12139-44.
Genome PropertyGenProp0781: gliding motility, Bacteroidetes type (HMM)