HMM Summary Page: TIGR03521

Functiongliding-associated putative ABC transporter substrate-binding component GldG
Gene SymbolgldG
Trusted Cutoff389.85
Domain Trusted Cutoff389.85
Noise Cutoff133.70
Domain Noise Cutoff133.70
Isology Typeequivalog
HMM Length552
AuthorSelengut J
Entry DateDec 18 2007 9:15AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldG is a protein linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldG abolish the gliding phenotype [1]. GldG, along with GldA and GldF are believed to compose an ABC transporter [1] and are observed as an operon. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.
ReferencesRN [1] RM PMID:11948149 RT Mutations in Flavobacterium johnsoniae gldF and gldG disrupt gliding motility and interfere with membrane localization of GldA. RA Hunnicutt DW, Kempf MJ, McBride MJ RL J Bacteriol. 2002 May;184(9):2370-8.
Genome PropertyGenProp0781: gliding motility, Bacteroidetes type (HMM)