HMM Summary Page: TIGR03518

Functiongliding motility-associated ABC transporter permease protein GldF
Gene SymbolgldF
Trusted Cutoff288.50
Domain Trusted Cutoff288.50
Noise Cutoff252.50
Domain Noise Cutoff252.50
Isology Typeequivalog
HMM Length240
AuthorSelengut J
Entry DateDec 14 2007 4:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldF is believed to be a ABC transporter permease protein (along with ATP-binding subunit, GldA and a sunstrate-binding subunit, GldG) and is linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldF abolish the gliding phenotype [1]. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.
ReferencesRN [1] RM PMID:11948149 RT Mutations in Flavobacterium johnsoniae gldF and gldG disrupt gliding motility and interfere with membrane localization of GldA. RA Hunnicutt DW, Kempf MJ, McBride MJ RL J Bacteriol. 2002 May;184(9):2370-8.
Genome PropertyGenProp0781: gliding motility, Bacteroidetes type (HMM)