HMM Summary Page: TIGR03516

Functionpeptidyl-prolyl isomerase, gliding motility-associated
Gene SymbolgldI
Trusted Cutoff157.60
Domain Trusted Cutoff157.60
Noise Cutoff101.20
Domain Noise Cutoff101.20
Isology Typeequivalog
HMM Length177
AuthorSelengut J
Entry DateDec 14 2007 3:38PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldI is a FKBP-type peptidyl-prolyl cis-trans isomerase (PF00254) linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockout of this gene abolishes the gliding phenotype [1]. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. This family is only found in Bacteroidetes containing the suite of genes proposed to confer the gliding motility phenotype.
ReferencesRN [1] RM PMID:15060031 RT GldI is a lipoprotein that is required for Flavobacterium johnsoniae gliding motility and chitin utilization. RA McBride MJ, Braun TF RL J Bacteriol. 2004 Apr;186(8):2295-302.
Genome PropertyGenProp0781: gliding motility, Bacteroidetes type (HMM)