HMM Summary Page: TIGR03490

Functionmycoides cluster lipoprotein, LppA/P72 family
Trusted Cutoff325.50
Domain Trusted Cutoff325.50
Noise Cutoff94.90
Domain Noise Cutoff94.90
Isology Typeparalog
HMM Length541
AuthorHaft DH
Entry DateOct 11 2007 9:32AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family occur in Mycoplasma mycoides, Mycoplasma hyopneumoniae, and related Mycoplasmas in small paralogous families that may also include truncated forms and/or pseudogenes. Members are predicted lipoproteins with a conserved signal peptidase II processing and lipid attachment site. Note that the name for certain characterized members, p72, reflects an anomalous apparent molecular weight, given a theoretical MW of about 61 kDa.
ReferencesRN [1] RM PMID:9004514 RT Characterization of the gene for an immunodominant 72 kDa lipoprotein of Mycoplasma mycoides subsp. mycoides small colony type. RA Cheng X, Nicolet J, Miserez R, Kuhnert P, Krampe M, Pilloud T, Abdo EM, Griot C, Frey J RL Microbiology. 1996 Dec;142 ( Pt 12):3515-24. RN [2] RM PMID:10512041 RT Comparative analysis of the lppA locus in Mycoplasma capricolum subsp. capricolum and Mycoplasma capricolum subsp. capripneumoniae. RA Monnerat MP, Thiaucourt F, Nicolet J, Frey J RL Vet Microbiol. 1999 Sep 15;69(3):157-72.