| Accession | TIGR03451 |
| Name | mycoS_dep_FDH |
| Function | S-(hydroxymethyl)mycothiol dehydrogenase |
| Trusted Cutoff | 512.90 |
| Domain Trusted Cutoff | 512.90 |
| Noise Cutoff | 512.15 |
| Domain Noise Cutoff | 512.15 |
| Isology Type | equivalog |
| EC Number | 1.1.1.306 |
| HMM Length | 358 |
| Mainrole Category | Cellular processes |
| Subrole Category | Detoxification |
| Gene Ontology Term | GO:0010127: mycothiol-dependent detoxification biological_process |
| | GO:0050607: mycothiol-dependent formaldehyde dehydrogenase activity molecular_function |
| Author | Haft DH |
| Entry Date | Jun 28 2007 5:16PM |
| Last Modified | Mar 1 2012 5:34PM |
| Comment | Members of this protein family are mycothiol-dependent formaldehyde dehydrogenase (EC 1.2.1.66). This protein is found, so far, only in the Actinobacteria (Mycobacterium sp., Streptomyces sp., Corynebacterium sp., and related species), where mycothione replaces glutathione. |
| References | RN [1]
RM PMID:9202149
RT Mycothiol, 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D- myo-inositol, is the factor of NAD/factor-dependent formaldehyde dehydrogenase.
RA Misset-Smits M, van Ophem PW, Sakuda S, Duine JA
RL FEBS Lett. 1997 Jun 9;409(2):221-2. |
| Genome Property | GenProp0923: mycothiol system (HMM) |
