| Accession | TIGR03446 |
| Name | mycothiol_Mca |
| Function | mycothiol conjugate amidase Mca |
| Gene Symbol | mca |
| Trusted Cutoff | 277.15 |
| Domain Trusted Cutoff | 277.15 |
| Noise Cutoff | 227.90 |
| Domain Noise Cutoff | 227.90 |
| Isology Type | equivalog |
| HMM Length | 283 |
| Mainrole Category | Cellular processes |
| Subrole Category | Detoxification |
| Author | Haft DH |
| Entry Date | Jun 27 2007 4:00PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Mycobacterium tuberculosis, Corynebacterium glutamicum, and related species use the thiol mycothiol in place of glutathione. This enzyme, homologous to the (dispensible) MshB enzyme of mycothiol biosynthesis, is described as an amidase that acts on conjugates to mycothiol. It is a detoxification enzyme. |
| References | RN [1]
RM PMID:14556638
RT Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase.
RA Steffek M, Newton GL, Av-Gay Y, Fahey RC
RL Biochemistry. 2003 Oct 21;42(41):12067-76. |
| Genome Property | GenProp0923: mycothiol system (HMM) |
