HMM Summary Page: TIGR03441

Functionurea transporter
Gene Symbolyut
Trusted Cutoff274.60
Domain Trusted Cutoff274.60
Noise Cutoff178.50
Domain Noise Cutoff178.50
Isology Typeequivalog
HMM Length292
Mainrole CategoryTransport and binding proteins
Subrole CategoryOther
Gene Ontology TermGO:0015204: urea transmembrane transporter activity molecular_function
GO:0015840: urea transport biological_process
GO:0016021: integral to membrane cellular_component
AuthorHaft DH
Entry DateJun 20 2007 11:30AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are bacterial urea transporters, found not only is species that contain urease, but adjacent to the urease operon. It was characterized in Yersinia pseudotuberculosis. Members are homologous to eukaryotic members of solute carrier family 14, a family that includes urea transporters, and to bacterial proteins in species with no detectable urea degradation system.
ReferencesRN [1] RM PMID:12180933 RT The Yersinia pseudotuberculosis Yut protein, a new type of urea transporter homologous to eukaryotic channels and functionally interchangeable in vitro with the Helicobacter pylori UreI protein. RA Sebbane F, Bury-Mone S, Cailliau K, Browaeys-Poly E, De Reuse H, Simonet M RL Mol Microbiol. 2002 Aug;45(4):1165-74.