HMM Summary Page: TIGR03440

Functionergothioneine biosynthesis protein EgtB
Gene SymbolegtB
Trusted Cutoff240.00
Domain Trusted Cutoff240.00
Noise Cutoff210.00
Domain Noise Cutoff210.00
Isology Typesubfamily
HMM Length406
AuthorHaft DH
Entry DateJun 19 2007 4:13PM
Last ModifiedJun 8 2012 12:26PM
CommentMembers of this family include EgtB, and enzyme of the ergothioneine biosynthesis, as found in numerous Actinobacteria. Characterized homologs to this family include a formylglycine-generating enzyme that serves as a maturase for an aerobic sulfatase (cf. the radical SAM enzymes that serve as anaerobic sulfatase maturases).
ReferencesRN [1] RM PMID:20420449 RT In vitro reconstitution of Mycobacterial ergothioneine biosynthesis. RA Seebeck FP RL J Am Chem Soc. 2010 May 19;132(19):6632-3.
Genome PropertyGenProp0752: ergothioneine biosynthesis (HMM)