HMM Summary Page: TIGR03428

Functionpermease, urea carboxylase system
Trusted Cutoff740.45
Domain Trusted Cutoff740.45
Noise Cutoff315.00
Domain Noise Cutoff315.00
Isology Typehypoth_equivalog
HMM Length475
AuthorHaft DH
Entry DateJun 13 2007 1:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentA number of bacteria obtain nitrogen by biotin- and ATP-dependent urea degradation system distinct from urease. The two characterized proteins of this system are the enzymes urea carboxylase and allophanate hydrolase, but other, uncharacterized proteins co-occur as genes encoded nearby in multiple organisms. This family includes predicted permeases of the amino acid permease family, likely to transport either urea or a compound from which urea is derived. It is found so far only Actinobacteria, whereas a number of other species with the urea carboxylase have an adjacent ABC transporter operon.