HMM Summary Page: TIGR03419

FunctionFeS cluster assembly scaffold protein NifU
Gene SymbolnifU
Trusted Cutoff187.90
Domain Trusted Cutoff187.90
Noise Cutoff181.15
Domain Noise Cutoff181.15
Isology Typeequivalog
HMM Length121
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0005198: structural molecule activity molecular_function
GO:0016226: iron-sulfur cluster assembly biological_process
AuthorHaft DH
Entry DateJun 5 2007 5:17PM
Last ModifiedFeb 14 2011 3:27PM
CommentNifU and NifS form a pair of iron-sulfur (FeS) cluster biosynthesis proteins much simpler than the ISC and SUF systems. Members of this protein family are a distinct group of NifU-like proteins, found always to a NifS-like protein and restricted to species that lack a SUF system. Typically, NIF systems service a smaller number of FeS-containing proteins than do ISC or SUF. Members of this particular branch typically are found, almost half the time, near the mnmA gene, involved in the carboxymethylaminomethyl modification of U34 in some tRNAs (see GenProp0704). While other NifU proteins are associated with nitrogen fixation, this family is not.
Genome PropertyGenProp0742: iron-sulfur cluster assembly NIF system (HMM)