HMM Summary Page: TIGR03415

Functioncholine ABC transporter, ATP-binding protein
Gene SymbolchoV
Trusted Cutoff483.75
Domain Trusted Cutoff483.75
Noise Cutoff428.45
Domain Noise Cutoff428.45
Isology Typeequivalog
HMM Length382
Mainrole CategoryTransport and binding proteins
Subrole CategoryAmino acids, peptides and amines
Gene Ontology TermGO:0015220: choline transmembrane transporter activity molecular_function
GO:0015871: choline transport biological_process
GO:0055052: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing cellular_component
AuthorHaft DH
Entry DateMay 24 2007 1:37PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the ATP-binding subunit of a three-protein transporter. This family belongs, more broadly, to the family of proline and glycine-betaine transporters, but members have been identified by direct characterization and by bioinformatic means as choline transporters. Many species have several closely-related members of this family, probably with variable abilities to act additionally on related quaternary amines.
ReferencesRN [1] RM PMID:15342567 RT The Sinorhizobium meliloti ABC transporter Cho is highly specific for choline and expressed in bacteroids from Medicago sativa nodules. RA Dupont L, Garcia I, Poggi MC, Alloing G, Mandon K, Le Rudulier D. RL J Bacteriol. 2004 Sep;186(18):5988-96.
Genome PropertyGenProp0748: choline ABC transporter, ChoXWV family (HMM)