HMM Summary Page: TIGR03409

Functionurea ABC transporter, permease protein UrtB
Gene SymbolurtB
Trusted Cutoff250.30
Domain Trusted Cutoff250.30
Noise Cutoff217.90
Domain Noise Cutoff217.90
Isology Typeequivalog
HMM Length291
Mainrole CategoryTransport and binding proteins
Subrole CategoryAmino acids, peptides and amines
Gene Ontology TermGO:0005887: integral to plasma membrane cellular_component
GO:0015840: urea transport biological_process
GO:0033221: urea-transporting ATPase activity molecular_function
GO:0055052: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing cellular_component
AuthorHaft DH
Entry DateMay 11 2007 5:12PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are ABC transporter permease proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity.
ReferencesRN [1] RM PMID: 11929526 RT An ABC-type, high-affinity urea permease identified in cyanobacteria. RA Valladares A, Montesinos ML, Herrero A, Flores E RL Mol Microbiol. 2002 Feb;43(3):703-15.
Genome PropertyGenProp0743: urea ABC transporter UrtABCDE (HMM)