| Accession | TIGR03407 |
| Name | urea_ABC_UrtA |
| Function | urea ABC transporter, urea binding protein |
| Gene Symbol | urtA |
| Trusted Cutoff | 492.75 |
| Domain Trusted Cutoff | 492.75 |
| Noise Cutoff | 378.35 |
| Domain Noise Cutoff | 378.35 |
| Isology Type | exception |
| HMM Length | 361 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Amino acids, peptides and amines |
| Gene Ontology Term | GO:0015840: urea transport biological_process |
| | GO:0030288: outer membrane-bounded periplasmic space cellular_component |
| | GO:0033219: urea binding molecular_function |
| | GO:0033221: urea-transporting ATPase activity molecular_function |
| | GO:0055052: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing cellular_component |
| Author | Haft DH |
| Entry Date | May 11 2007 2:58PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are ABC transporter substrate-binding proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. Members of this protein family tend to have the twin-arginine signal for Sec-independent transport across the plasma membrane. |
| References | RN [1]
RM PMID: 11929526
RT An ABC-type, high-affinity urea permease identified in cyanobacteria.
RA Valladares A, Montesinos ML, Herrero A, Flores E
RL Mol Microbiol. 2002 Feb;43(3):703-15. |
| Genome Property | GenProp0743: urea ABC transporter UrtABCDE (HMM) |
