Accession | TIGR03395 |
Name | sphingomy |
Function | sphingomyelin phosphodiesterase |
Gene Symbol | sph |
Trusted Cutoff | 248.20 |
Domain Trusted Cutoff | 248.20 |
Noise Cutoff | 178.80 |
Domain Noise Cutoff | 178.80 |
Isology Type | equivalog |
EC Number | 3.1.4.12 |
HMM Length | 286 |
Mainrole Category | Cellular processes |
Subrole Category | Pathogenesis |
Gene Ontology Term | GO:0004767: sphingomyelin phosphodiesterase activity molecular_function |
Author | Haft DH |
Entry Date | Apr 25 2007 2:58PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this family are bacterial proteins that act as sphingomyelin phosphodiesterase (EC 3.1.4.12), also called sphingomyelinase. Some members of this family have been shown to act as hemolysins. |
References | RM PMID: 2163985
RT Molecular analysis of a sphingomyelinase C gene from Leptospira interrogans serovar hardjo.
RA Segers RP, van der Drift A, de Nijs A, Corcione P, van der Zeijst BA, Gaastra W
RL Infect Immun. 1990 Jul;58(7):2177-85. |