HMM Summary Page: TIGR03394

Functionindolepyruvate/phenylpyruvate decarboxylase
Gene SymbolipdC
Trusted Cutoff554.50
Domain Trusted Cutoff554.50
Noise Cutoff464.60
Domain Noise Cutoff464.60
Isology Typeequivalog
EC Number4.1.1.74
HMM Length535
AuthorHaft DH
Entry DateApr 25 2007 1:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentA family of closely related, thiamine pyrophosphate-dependent enzymes includes indolepyruvate decarboxylase (EC, phenylpyruvate decarboxylase (EC, pyruvate decarboxylase (EC, branched-chain alpha-ketoacid decarboxylase, etc.. Members of this group of homologs may overlap in specificity. This model represents a clade that includes a Azospirillum brasilense member active as both phenylpyruvate decarboxylase and indolepyruvate decarboxylase.
ReferencesRN [1] RM PMID: 17403037 RT The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. RA Versees W, Spaepen S, Vanderleyden J, Steyaert J RL FEBS J. 2007 May;274(9):2363-75.