Accession | TIGR03393 |
Name | indolpyr_decarb |
Function | indolepyruvate decarboxylase |
Gene Symbol | ipdC |
Trusted Cutoff | 946.00 |
Domain Trusted Cutoff | 946.00 |
Noise Cutoff | 696.00 |
Domain Noise Cutoff | 696.00 |
Isology Type | equivalog |
EC Number | 4.1.1.74 |
HMM Length | 539 |
Mainrole Category | Central intermediary metabolism |
Subrole Category | Other |
Gene Ontology Term | GO:0009684: indoleacetic acid biosynthetic process biological_process |
| GO:0047434: indolepyruvate decarboxylase activity molecular_function |
Author | Haft DH |
Entry Date | Apr 25 2007 10:02AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | A family of closely related, thiamine pyrophosphate-dependent enzymes includes indolepyruvate decarboxylase (EC 4.1.1.74), phenylpyruvate decarboxylase (EC 4.1.1.43), pyruvate decarboxylase (EC 4.1.1.1), branched-chain alpha-ketoacid decarboxylase, etc.. Members of this group of homologs may overlap in specificity. Within the larger family, this model represents a clade of bacterial indolepyruvate decarboxylases, part of a pathway for biosynthesis of the plant hormone indole-3-acetic acid. Typically, these species interact with plants, as pathogens or as beneficial, root-associated bacteria. |
References | RN [1]
RM PMID: 12752451
RT Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid.
RA Schutz A, Sandalova T, Ricagno S, Hubner G, Konig S, Schneider G
RL Eur J Biochem. 2003 May;270(10):2312-21. |