| Accession | TIGR03379 |
| Name | glycerol3P_GlpC |
| Function | glycerol-3-phosphate dehydrogenase, anaerobic, C subunit |
| Gene Symbol | glpC |
| Trusted Cutoff | 279.90 |
| Domain Trusted Cutoff | 279.90 |
| Noise Cutoff | 222.45 |
| Domain Noise Cutoff | 222.45 |
| Isology Type | equivalog |
| EC Number | 1.1.5.3 |
| HMM Length | 397 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Anaerobic |
| Gene Ontology Term | GO:0006071: glycerol metabolic process biological_process |
| | GO:0009331: glycerol-3-phosphate dehydrogenase complex cellular_component |
| | GO:0051536: iron-sulfur cluster binding molecular_function |
| Author | Haft DH |
| Entry Date | Apr 2 2007 4:05PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. |
| References | RN [1]
RM PMID: 3286606
RT Nucleotide sequence and gene-polypeptide relationships of the glpABC operon encoding the anaerobic sn-glycerol-3-phosphate dehydrogenase of Escherichia coli K-12.
RA Cole ST, Eiglmeier K, Ahmed S, Honore N, Elmes L, Anderson WF, Weiner JH
RL J Bacteriol. 1988 Jun;170(6):2448-56. |
| Genome Property | GenProp0737: anaerobic glycerol-3-phosphate dehydrogenase complex (HMM) |
