HMM Summary Page: TIGR03375

Functiontype I secretion system ATPase
Trusted Cutoff693.10
Domain Trusted Cutoff693.10
Noise Cutoff586.85
Domain Noise Cutoff586.85
Isology Typesubfamily
HMM Length696
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
AuthorHaft DH
Entry DateMar 27 2007 1:34PM
Last ModifiedFeb 14 2011 3:27PM
CommentType I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export.
Genome PropertyGenProp0059: type I secretion (HMM)