HMM Summary Page: TIGR03373

Functiontype VI secretion-associated protein, BMA_A0400 family
Trusted Cutoff41.20
Domain Trusted Cutoff41.20
Noise Cutoff33.70
Domain Noise Cutoff33.70
Isology Typehypoth_equivalog_domain
HMM Length136
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
AuthorHaft DH
Entry DateMar 26 2007 4:51PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are found exclusively, although not universally, in bacterial species that possess a type VI secretion system. Genes are found in type VI secretion-associated gene clusters. The specific function is unknown. This model represents the rather well-conserved amino-terminal domain of a protein family in which carboxy-terminal regions, when present, show little conservation.
ReferencesRN [1] RM PMID: 16432199 RT Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system. RA Pukatzki S, Ma AT, Sturtevant D, Krastins B, Sarracino D, Nelson WC, Heidelberg JF, Mekalanos JJ RL Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1528-33.
Genome PropertyGenProp0735: type VI secretion (HMM)