HMM Summary Page: TIGR03371

AccessionTIGR03371
Namecellulose_yhjQ
Functioncellulose synthase operon protein YhjQ
Gene SymbolyhjQ
Trusted Cutoff157.85
Domain Trusted Cutoff157.85
Noise Cutoff104.25
Domain Noise Cutoff104.25
Isology Typeequivalog
HMM Length246
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0005575: cellular_component cellular_component
GO:0030243: cellulose metabolic process biological_process
AuthorHaft DH
Entry DateMar 26 2007 10:02AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are the YhjQ protein, found immediately upsteam of bacterial cellulose synthase (bcs) genes in a broad range of bacteria, including both copies of the bcs locus in Klebsiella pneumoniae. In several species it is seen clearly as part of the bcs operon. It is identified as a probable component of the bacterial cellulose metabolic process not only by gene location, but also by partial phylogenetic profiling, or Haft-Selengut algorithm (PMID:16930487), based on a bacterial cellulose biosynthesis genome property profile. Cellulose plays an important role in biofilm formation and structural integrity in some bacteria. Mutants in yhjQ in Escherichia coli, show altered morphology an growth, but the function of YhjQ has not yet been determined.
ReferencesDR PFAM; PF01656; CobQ/CobB/MinD/ParA nucleotide binding domain RN [1] RM PMID: 12382054 RT The effect of a disrupted yhjQ gene on cellular morphology and cell growth in Escherichia coli. RA Kim MK, Park SR, Cho SJ, Lim WJ, Ryu SK, An CL, Hong SY, Park YW, Kahng GG, Kim JH, Kim H, Yun HD RL Appl Microbiol Biotechnol. 2002 Oct;60(1-2):134-8. RN [2] RM PMID: 16930487 RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic. RA Haft DH, Paulsen IT, Ward N, Selengut JD RL BMC Biol. 2006 Aug 24;4:29.
Genome PropertyGenProp0658: cellulose biosynthesis (HMM)