HMM Summary Page: TIGR03345

Functiontype VI secretion ATPase, ClpV1 family
Gene SymbolclpV
Trusted Cutoff884.95
Domain Trusted Cutoff884.95
Noise Cutoff881.25
Domain Noise Cutoff881.25
Isology Typeequivalog
HMM Length852
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0033103: protein secretion by the type VI secretion system biological_process
GO:0033104: type VI protein secretion system complex cellular_component
GO:0042623: ATPase activity, coupled molecular_function
AuthorHaft DH
Entry DateMar 14 2007 1:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system.
ReferencesRN [1] RM PMID: 16763151 RT A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus. RA Mougous JD, Cuff ME, Raunser S, Shen A, Zhou M, Gifford CA, Goodman AL, Joachimiak G, Ordonez CL, Lory S, Walz T, Joachimiak A, Mekalanos JJ RL Science. 2006 Jun 9;312(5779):1526-30.
Genome PropertyGenProp0735: type VI secretion (HMM)