HMM Summary Page: TIGR03342

Functionsulfur relay protein, TusE/DsrC/DsvC family
Gene SymboltusE
Trusted Cutoff53.50
Domain Trusted Cutoff53.50
Noise Cutoff40.95
Domain Noise Cutoff40.95
Isology Typesubfamily
HMM Length108
AuthorHaft DH
Entry DateMar 12 2007 5:21PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family may be described as TusE, a partner to TusBCD in a sulfur relay system for 2-thiouridine biosynthesis, a tRNA base modification process. Other members are DsrC, a functionally similar protein in species where the sulfur relay system exists primarily for sulfur metabolism rather than tRNA base modification. Some members of this family are known explicitly as the gamma subunit of sulfite reductases.
ReferencesDR PFAM; PF04358; DsrC; DsrC like protein RN [1] RM PMID: 16387657 RT Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions. RA Ikeuchi Y, Shigi N, Kato J, Nishimura A, Suzuki T RL Mol Cell. 2006 Jan 6;21(1):97-108.
Genome PropertyGenProp0654: intracellular sulfur oxidation (HMM)